JAMA NetworkAdult-Onset Genetic Central Nervous System Disorders Masquerading as Acquired Neuroinflammatory Disorders: A Review

Adult-onset genetic disorders may present with clinical and brain imaging features suggestive of acquired inflammatory diseases. An ever-growing number of potentially treatable adult-onset genetic neuroinflammatory disorders have been described in the past few years that need to be rapidly identified. This review aims to provide insights to neurologists so they can confirm a diagnosis early, when some of these genetic disorders can be successfully treated.