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Journal of Clinical OncologyAssociation of Circulating Tumor DNA Dynamics w. Clinical Outcomes in the Adjuvant Setting for Patients w. CRC from an Observational GALAXY Study in CIRCULATE – Japan

Circulating tumor DNA (ctDNA)-based molecular residual disease (MRD) might be used to identify patients who would benefit more from standard-of-care adjuvant chemotherapy by accurately assessing recurrence-risk post-surgery and by evaluating adjuvant chemotherapy efficacy. This analysis from the GALAXY study, an observational study monitoring MRD, evaluates the association of ctDNA dynamics with a short-term clinical outcome and ACT efficacy.