Epoch HealthCaffeine Intake Linked to Lower Risk of Multiple Cardiometabolic Diseases

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Recent research suggests that moderate caffeine intake may offer protection against cardiometabolic multimorbidity (CM), defined as having two or more disorders affecting the heart or metabolism. The study, published in The Journal of Clinical Endocrinology & Metabolism, analyzed data from more than 360,000 participants in the UK Biobank study, finding an inverse relationship between caffeine consumption and the risk of developing CM.

Key Points:

• Moderate caffeine intake (200-300 mg per day) was associated with a 40.7% lower risk of new-onset CM compared to non-consumers or those consuming less than 100 mg daily.
• Moderate coffee consumption (three cups per day) showed a 48.1% decrease in the risk of new-onset CM.
• The study found an inverse relationship between caffeine intake and the development of single cardiometabolic diseases, as well as protection against progression to CM.
• Participants with CM had a four- to seven-times increased risk of all-cause mortality compared to those without cardiometabolic disease.
• Caffeine sources in the study were primarily from dietary intake (coffee, tea) rather than supplements.
• High caffeine intake and caffeine sensitivity can lead to adverse effects, including heart rhythm disorders and increased blood pressure.
• For individuals with existing heart disease, moderation and consultation with a physician are advised when considering caffeine intake.

Although this study focuses on caffeine’s potential benefits, it’s worth noting that excessive caffeine intake can have negative health effects. According to the FDA, consuming 1,200 mg of caffeine (about 12 cups of coffee) in a short time can lead to toxic effects such as seizures.

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