A Deep Dive into the Interplay between Fungal Infections and Oncogenesis
In an era where cancer continues to pose significant health challenges globally, understanding its multifaceted origins is crucial. One such origin, explored in a recent study, is the potential link between fungal infections and cancer development.
HCN Medical Memo
Understanding this potential link between fungal infections and cancer development could open new avenues for early detection and prevention strategies. It underscores the importance of monitoring patients with persistent fungal infections, especially those who are immunocompromised.
- A 2021 study in the Advanced Pharmaceutical Bulletin (APB) presents epidemiological evidence of a clear association between fungal infections and cancer development.
- This link is often observed in immunocompromised individuals, such as those with AIDS.
- Fungal infections can produce carcinogenic chemicals like acetaldehyde, which can damage DNA and inhibit its repair.
- The most common fungi species involved in cancer include Candida albicans, C. tropicalis, C. glabrata, Fusarium verticillioides, F. proliferatum, Aspergillus flavus, and A. parasiticus.
In 2018, 18.1 million new cases of cancer occurred worldwide, with 9.5 million lives lost to it. Experts predict the number of new cases will soar to 29.5 million by 2040 and cancer-related deaths to 16.4 million.
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