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Journal of Clinical OncologyLongitudinal Molecular Profiling of Circulating Tumor Cells in Metastatic Renal Cell Carcinoma

The authors determined the prognostic significance of CTC enumeration and the evolution of both CTC enumeration and the HP ratio over time in the largest longitudinal CTC study in mRCC to date. Potential biomarkers to predict and track response to immunotherapy in mRCC are provided by these insights into changes in both tumor burden and the molecular profile of tumor cells in response to various treatments.

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