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Practical NeurologyNew TBI Care Guidelines Released by ACS


The American College of Surgeons has released updated Best Practices Guidelines for TBI management, expanding on their 2015 recommendations. This comprehensive revision introduces new protocols for neuroimaging, blood-based biomarkers, pharmacologic management, rehabilitation, and postacute care. The guidelines, developed through expert consensus and evidence review, now include specific considerations for pediatric and geriatric populations.

Key Points:

  • Advanced imaging protocols now specify optimal timing for CT and MRI usage in pediatric and adult patients, with emphasis that negative CT scans do not definitively rule out TBI
  • Blood-based biomarkers (GFAP, UCH-L1, S100B) are now recommended for evaluating CT necessity and predicting 6-month recovery outcomes
  • Pharmacologic management guidelines detail specific protocols for antiseizure medications to prevent posttraumatic seizures, along with antiplatelet and anticoagulant therapy strategies
  • Integration of trauma and rehabilitation services is emphasized as crucial for optimal recovery trajectories
  • New sections address care protocols for patients with GCS scores 13-15, outcome assessment metrics, and structured TBI education and follow-up procedures

HCN Medical Memo
These guidelines represent a significant shift toward precision medicine in TBI care, incorporating molecular diagnostics while maintaining practical clinical applicability across various healthcare settings.


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