In a cluster-randomized trial conducted across multiple countries, a multicomponent clinical intervention was evaluated for the management of postpartum hemorrhage in patients undergoing vaginal delivery. The intervention involved the use of a calibrated blood-collection drape for early detection of postpartum hemorrhage and a treatment bundle consisting of various interventions. The study found that the intervention group had a lower risk of severe postpartum hemorrhage, laparotomy for bleeding, or death from bleeding compared to the usual-care group. The intervention group also had higher rates of postpartum hemorrhage detection and adherence to the treatment bundle.