Articles related to CAR T-CELL THERAPIES

Discover how base editing via CRISPR-guided cytidine deamination could revolutionize CAR T-cell therapy for T-cell cancers, offering a promising approach to treating relapsed or refractory cases in pediatric patients.

The rapid exhaustion of T cells upon encountering a tumor, as revealed in a recent study, challenges existing theories and may have profound implications for cancer immunotherapies. Explore the findings to understand how this discovery could influence the future of personalized treatment.

The recent approval of epcoritamab for R/R DLBCL introduces a new pathway in treatment, offering substantial response rates and the potential for broader implementation beyond academic centers. Explore the detailed insights into the function, efficacy, and prospective implications of this novel therapy.

Researchers at Roswell Park Comprehensive Cancer Center have unveiled a novel approach using bispecific T-cell engagers (BiTEs) to enhance immune responses against ovarian cancer. This promising pathway may lead to improved therapeutic options for patients unresponsive to conventional immunotherapies.

The phase 3 study evaluating cilta-cel, a BCMA–directed CAR T-cell therapy, in patients with lenalidomide-refractory multiple myeloma indicates promising results in progression-free survival and overall response rates.

Join this crucial journey to broaden your comprehension of CAR T-cell therapy, CRS and ICANS management, and learn how to utilize this knowledge for better patient outcomes in the battle against relapsed/refractory multiple myeloma.