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JAMA Network
Gabapentin has been increasingly used as part of a multimodal analgesia regimen to reduce opioid use in perioperative pain management. In this cohort study of 237,872 adults aged 65 years or older, perioperative gabapentin users had significantly increased risk of delirium, new antipsychotic use, and pneumonia compared with nonusers after major surgery.
Anesthesiology October 3rd 2022
Annals of Internal Medicine
In a study involving 212 adults with symptomatic knee osteoarthritis, an unsupervised online yoga program delivered via prerecorded videos over 12 weeks netted improved physical function vs. the control group. At 12 weeks, knee stiffness, quality of life, and arthritis self-efficacy improved more with yoga than the control intervention. Benefits were not maintained at 24 weeks. Adverse events were minor.
Family Medicine/General Practice September 26th 2022
ACP Internist
The VITAL trial enrolled more than 25,000 men and women over age 50. Supplemental vitamin D showed no significant benefit vs. placebo in preventing the common fractures of osteoporosis.
Geriatrics August 10th 2022
Given the high burden of shoulder conditions, clinicians should pay attention to any factors that may further increase risks. This study found a low incidence of shoulder issues following vaccination in the deltoid muscle but does delineate population at higher risk for developing these issues.
Family Medicine/General Practice March 29th 2022