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British Medical Journal (The BMJ)
Explore how metformin, a widely accessible diabetes drug, might play a critical role in preventing long COVID when given during the acute phase of COVID-19.
Allergy & Immunology June 21st 2023
Annals of Internal Medicine
Let’s delve into the complexity of mask effectiveness against SARS-CoV-2 in diverse settings. Debate rages on about optimal mask use for COVID-19 prevention. This trial takes a fresh look at the issue. It evaluates N95, surgical, and cloth masks in preventing SARS-CoV-2 infections. The team sourced data from MEDLINE, EMBASE, and medRxiv. They also scanned relevant reference lists. They selected randomized trials and observational studies. These studies increased mask use and controlled for confounding factors in assessing SARS-CoV-2 infection risk. Two investigators carried out the data extraction process. They carefully abstracted data from each study and evaluated its quality. Their efforts resulted in the inclusion of three randomized trials and 21 observational studies. Evidence from two trials and seven studies points to a possible reduction in SARS-CoV-2 infection risk through mask use in community settings. Despite this, observational studies failed to provide sufficient evidence for other mask comparisons due to methodological inconsistencies. In routine patient care settings, one new trial and four studies indicated comparable infection risk between surgical masks and N95 respirators. However, the study couldn’t disregard the potential beneficial effects of N95 respirators. Yet, several limitations cloud these findings. These include a limited number of randomized trials, methodological […]
All Specialties May 24th 2023
MDLinx
The outbreak of blastomycosis was first noted in early March when several individuals from the plant were diagnosed with atypical pneumonias. The mill was idled for several weeks to be disinfected, but the source of the infection was never located.
Allergy & Immunology May 11th 2023
Eyewire+
Infection patients reported using more than ten different brands of artificial tears, and some patients used multiple brands. The majority of patients who used artificial tears said they used EzriCare Artificial Tears, an over-the-counter, preservative-free product packaged in multidose bottles. The outbreak strain was found in opened EzriCare bottles with different lot numbers collected from two states, according to CDC laboratory testing.
Infectious Diseases February 27th 2023
A detailed summarization of the clinical presentation of 197 individuals with PCR-confirmed diagnosis of monkeypox in the UK. The summary documents a highly variable prodrome in terms of prodromal symptoms and timing to eruption of visible lesions. Systemic illness was seen in 86% of patients. After mucocutaneous lesions, seen in 100% of patients, fever was the next most common manifestation, seen in 62% of patients.
All Specialties August 4th 2022
“The original misnomer for HIV—gay-related immune deficiency (GRID)—looms large in the consciousness of many gay men and offers a cautionary lesson for monkeypox and other infectious disease outbreaks.”
All Specialties July 7th 2022