
Emerging research from the Atherosclerosis Risk in Communities (ARIC) study, involving more than 6,000 participants over 25 years, highlights the significant impact of flossing on reducing stroke risk. The study’s observational nature and reliance on self-reported data warrant cautious interpretation.
Key Clinical Considerations:
- Ischemic Stroke Risk: Flossing at least once a week reduces ischemic stroke risk by 22%.
- Cardio-embolic Stroke Risk: A 44% reduction in cardio-embolic stroke risk is associated with regular flossing.
- AFib Incidence: Flossing lowers the incidence of atrial fibrillation by 12%.
- Oral-Systemic Health: Flossing prevents periodontal disease, reducing inflammation and atherosclerosis.
- Study Limitations: Self-reported data and observational design limit causation claims.

HCN Medical Memo
Encouraging patients to floss regularly can be a practical, low-cost adjunct to stroke prevention strategies. This recommendation should complement established measures like blood pressure control and lifestyle modifications. Further research, especially randomized controlled trials, is needed to confirm these findings and explain causal pathways.
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