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Psych Congress NetworkTMS Shows Promise in Effective Obsessive-Compulsive Disorder Treatment

There was a significant reduction in Yale-Brown Obsessive-Compulsive Scale (Y-BOCS) score in the active TMS group.

A recent systematic review and meta-analysis has shed light on the potential of transcranial magnetic stimulation (TMS) in treating obsessive-compulsive disorder (OCD). The study examines the efficacy of TMS, exploring various brain targets and protocols, and emphasizes the need for further research to pinpoint the optimal approach.

Key Points:

  • Systematic review and meta-analysis of 31 trials, including open trials, randomized controlled trials, and single- or double-blind trials.
  • Specific brain targets like the right orbitofrontal cortex (OFC) showed more promising results.
  • TMS represents a safe and effective treatment option for OCD, according to the authors.

Additional Points:

  • The precise neural target and protocol for TMS in OCD treatment remain subjects of debate.
  • High rates of unresponsiveness to conventional treatments (40-60%) make TMS an appealing alternative.
  • The study calls for future controlled multicenter trials to compare different targets and protocols.


  • Although TMS shows promise in OCD treatment, further research is needed to establish clear indications of a specific protocol or brain target.

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Did You Know?
OCD affects approximately 1-2% of the population, making it one of the more common psychiatric disorders. Treatment can be challenging, with traditional methods often proving ineffective for a significant portion of those affected, underscoring the importance of exploring alternative therapies like TMS.

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