Neo-adjuvant therapy with nivolumab and ipilimumab is associated with a high pCR rate in ptsd with MSI/dMMR resectable OGA.

When tested in mice with pancreatic cancer, a BET inhibitor/anti-PD-1 combination prevented neoplastic transformation induced by the oncogene KRAS, increased survival and increased the recruitment of cytotoxic T-cells to the tumor.

The phase 3 RATIONALE 306 trial of tislelizumab plus chemotherapy significantly improved OS compared to chemotherapy alone in patients with previously untreated advanced esophageal squamous cell carcinoma.

Although vaccinations to the arm can still prevent serious illness, their ability to ward off infection completely has been diminished. And part of the reason may be the location of the vaccines, which some scientists now want to change by delivering inoculations to the site where the virus first makes contact: the nose. Three separate nasal sprays, now in advanced trials, could trigger stronger immune responses in people who have COVID-19.

How does the diagnostic performance of home antigen tests change during the course of SARS-CoV-2 infection? Symptomatic individuals with an initial negative home antigen test result for SARS-CoV-2 infection should test again one to two days later because test sensitivity seems to peak several days after illness onset.

Cannabis use increases the likelihood that patients will develop several negative health conditions, such as insomnia, anxiety, psychosis, and depression. As such, cannabis use should be prescribed carefully by physicians.