Despite aggressive therapy, the 5-year survival rate for patients with metastatic or recurrent rhabdomyosarcoma – the most common soft tissue sarcoma of childhood – remains poor, and beyond PAX-FOX01 fusion status, no genomic markers are available for risk stratification. This international consortium study was designed to determine the incidence of driver mutations and their association with clinical outcome.

It is important for young people, caregivers, and healthcare providers to recognize possible symptoms of colorectal cancer (CRC) and arrange a colonoscopy or other tests when necessary. This article presents a thorough review of CRC and its impact on young patients, including a hypothesis for the increase of cases, screening recommendations, demographic features, symptoms, and recommendations for physicians.

This Original Investigation from JAMA Network Open assesses whether clinically used markers of breast cancer, such as tumor size, tumor grade, progesterone receptor status, and Ki-67 status, are associated with long-term (25-year) survival as they are with short-term survival. The study was a secondary analysis of data from a subset of 565 women who participated in the Stockholm tamoxifen (STO-3) trial from 1976 to 1990.

In this article/podcast from KevinMD.com, the author encourages readers to make some adjustments in their life to reduce the professional and personal risks associated with the stakeholders who target physicians, including corporate America, the government, patients, and the financial industry. The commentary is a response to President Biden’s multi-trillion spending plan, which targets rich corporations and wealthy individual Americans making more than $400,000.

Poker is a game of chance and strategy that demands many skills, whether it’s reading a situation, making the appropriate bet, dealing with difficult decisions, or dealing with uncertainty. All of these situations mirror the daily decisions doctors are required to make, and whether you’re a novice at the table or a regular player, here are seven circumstances in the game of poker that can be teaching moments for the physician.

The recommendations from the American Academy of Pediatrics (AAP) are an update to the group’s 2012 policy statement in an effort to better equip physicians with the necessary knowledge to accurately screen, evaluate, and manage the risk of both sudden cardiac arrest (SCA) and sudden cardiac death (SCD) in youth. Screening for all children, regardless of athletic status, should be completed at least every three years.