Bookmark this page – or download the information directly, if you prefer – to ensure you’re always connected to the latest and greatest information on the very best in NSCLC treatment regimens (NCCN Guidelines).

Source: Blood AdvancesKey Points: In a cohort of 154 patients with NHL or MM receiving CAR T-cells, clonal hematopoiesis of indeterminate potential (CHIP) was present in 48%. Although associated with worse prognosis in these patients receiving autologous transplantation, no such association was seen in these patients receiving CAR T. Instead, the authors saw increased rates of complete response and cytokine release syndrome severity in the younger than 60 population. However, there was no difference in progression-free or overall survival, regardless of age. Design: Cohort review of 154 patients with NHL or MM receiving CAR T-cells

This version of the carboplatin AUC calculator includes a standard multi-clearance output to help you make an informed decision in determining an appropriate final carboplatin dose. Added bonus? Be sure to check the link to the “new version,” which includes the CKD-EPI equation (corrected for BSA) as an additional clearance equation.

MDCalc.com offers this helpful tool, which calculates creatinine clearance (CrCl) according to the Cockcroft-Gault equation. The tool also allows height input, which analyzes BMI and provides a modified estimate and range.

Source: BMC Pulmonary MedicineFindings:  IPF patients who switched from one antifibrotic therapy to the alternative — whether from pirfenidone (Esbriet) to nintedanib (Ofev, Vargatef) or the other way around – had improved survival. This observation held true whether the reason for switch was disease progress or tolerance issues.Design: Multi-center retrospective cohort study; 262 patients

Often undiagnosed due to its unspecific symptoms, hereditary angioedema (HAE) is a tricky condition that causes many patients unnecessary suffering with unnecessary surgeries and invasive diagnostic/therapeutic interventions. Read on to educate yourself on some of the alarming numbers on the orphan disease.