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British Medical JournalArtificial Sweeteners and Risk of Cardiovascular Diseases: Results from the Prospective NutriNet-Santé Cohort

In a prospective study following the diet and activity records of more than 100,000 individuals in France, artificial sweeteners were positively correlated with cardiovascular diseases. Analyzing 900,000 person-years of data showed:

  • Total artificial sweetener intake was associated with CVD risk
  • Artificial sweeteners were more strongly associated with cerebrovascular disease
  • Aspartame was associated with increase cerebrovascular events
  • Acesulfame K and sucralose were associated with increased coronary heart disease risk