Among 150 people ages 65 to 88, investigational transcranial alternating current stimulation for 20 minutes over 4 consecutive days produced selective improvements in working and long-term memory in older adults that lasted for at least a month The rate of memory improvement over 4 days predicted the size of memory benefits 1 month later, the researchers found. Moreover, people with lower baseline cognitive function experienced larger and longer lasting memory improvements.
“We found that by applying extremely weak electrical current safely and noninvasively to the prefrontal cortex at a high frequency, we could selectively improve long-term memory in older people aged 65 to 88 years old without changing short-term memory.”
Robert Reinhart, PhD, Boston University in Nature Neuroscience