Articles related to Hematology/Oncology

DLBCL is increasingly being recognized as a heterogeneous disease with distinct molecular subtypes. This has challenged the rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) treatment paradigm in recent years, as several DLBCL subtypes have inferior survival after standard R-CHOP therapy. So how do you choose? In this review the authors conclude with proposed clinical management scenarios in which DA-R-EPOCH may be preferred, including some for patient populations in which the use of R-CHOP vs. DA-R-EPOCH is controversial.

Clinical Advances in Hematology & Oncology talks with Sonali M. Smith, MD, an Elwood V. Jensen Professor in Medicine and Chief, Section of Hematology/Oncology at the University of Chicago, about all things transformed lymphoma, including risk factors, distinguishing characteristics, pathogenesis, traditional treatment approaches, treatment goals, new treatment strategies, and other promising areas of research.

A good primer for the oncologist on several cancer screening tests that can be administered at home and help detect cancer in its earliest, most treatable stages — often before people experience symptoms. Some tests, such as a screening colonoscopy, can even treat cancer by removing abnormal cells before they become problematic.

The incredible story of how a young mother of two children survived and ultimately overcame colon cancer that had spread throughout her body. Despite suffering severe anemia, diarrhea and emesis, and losing 25 pounds, this determined woman beat the odds.

This Children’s Oncology Group report recommends new guidance on administering radiotherapy among children with cancer. Questions are answered around imaging protocols, dose reduction, setup correction, and adaptive therapy.

A study published in Blood Advances finds that higher levels of NETosis in myeloproliferative neoplasms (MPNs) are not linked to thrombotic events. The study determined that while NETosis may play a role in facilitating thrombosis, it is not a sole causative determinant in MPN-associated thrombophilia.