Articles related to Internal Medicine

In this podcast/article from KevinMD, the story of Dr. Hasan Gokal is examined, a Houston physician who was fired from his public health job and was subsequently faced with criminal charges for stealing a vial of the vaccine. His case was also brought to the Texas Medical Board. In a sea of regulations and protocols, were his actions well-intentioned and in the best interest of patient care and safety?

The approval of the drug (Fotivda, Aveo Pharmaceuticals) was based on the results of the open-label, multi-center TIVO-3 trial, which looked at progression-free survival (PFS) as the main efficacy endpoint, assessed by a blinded independent radiology review committee. Secondary end points included overall survival (OS) and objective response rate (ORR).

This article from Radiopaedia discusses inclusions, usage, assessment of treatment response, caveats, history, and etymology of the internationally recognized Deauville five-point scale (Deauville 5PS), which was proposed in an international workshop attended by hematologists and nuclear medicine specialists in Deauville, France in 2009.

More good news for zanubrutinib, which received accelerated approval in November 2019 in the US for the treatment of mantle cell lymphoma (MCL) in adult patients who have undergone at least one prior therapy. The supplemental new drug application (sNDA) was submitted by the drug’s manufacturer, BeiGene, based on data from the global phase III ASPEN trial.

Without a centralized scheduling system and 50 states to consider, scheduling a COVID-19 vaccine appointment online isn’t so simple. Thankfully, others with scheduling savvy and a little patience have put together some advice. We invite you to share these tips with your patients struggling to get an appointment and how to handle the technology, processes, and preparation.

In this podcast/article from KevinMD, the implications of long COVID (the symptoms occurring more than three weeks after infection, also known as post-acute COVID syndrome) – specifically focused on post-viral fatigue syndrome (PVFS) – are examined, as the inability to tolerate a glass of wine or a bottle of beer could be an important clue to its true diagnosis.