Articles related to Pediatrics

Although most skin problems are harmless, a minor one can become serious in people who have diabetes. Whether it’s the common skin tag or more tongue-twisting things like necrobiosis lipoidica, you should be aware of the dermatologic conditions that could be precursors or signs of diabetes in your patients. With images and descriptions, this resource will provide a great review of the conditions.

The data was presented to the FDA, which reported 789 cases of myocarditis/pericarditis – predominantly in males – after receiving the Pfizer/BioNTech and Moderna vaccines, most commonly after the second dose. Symptoms included chest pain, elevated cardiac enzymes, ST or T wave changes, dyspnea, and abnormal echocardiography/imaging for those ages 30 years and younger.

It’s a battle of two heavyweights in this trial report from the Journal of Clinical Oncology, sharing the results of acalabrutinib (Calquence) compared to ibrutinib (Imbruvica) in treating chronic lymphocytic leukemia (CLL). Selected events of clinical interest included cardiac events, atrial fibrillation, ventricular tachyarrhythmias, hypertension, bleeding and major bleeding events, infections, and second primary malignancies excluding non-melanoma skin cancers.

Are you biased toward certain types of patients? “Sometimes” is likely your answer, but there are implicit biases that doctors may not be aware they have. To help answer this question, Medscape put together a survey to weigh these biases, with emotional problems coming in at No. 1. Whether they are implicit or explicit, here are the other patient characteristics that commonly trigger a predisposition in doctors. 

Since April 2021, there have been reports of myocarditis and/or pericarditis after receipt of an m-RNA COVID-19 vaccine, according to the Centers for Disease Control and Prevention (CDC) . Most cases have been among male adolescents and young adults ages 16 and older, typically occurring within several days after the second dose of m-RNA COVID-19 vaccine.

In this Original Report from the Journal of Clinical Oncology, the authors conducted a phase I trial of autologous CD19 CAR T cells in children and young adults (CAYAs) with relapsed or refractory B-cell acute lymphoblastic leukemia (B-ALL) to discover whether the role for allogeneic hematopoietic stem-cell transplant (alloHSCT) following CD19-CAR T-cell therapy can improve long-term outcomes.