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Annals of Internal MedicineLeft Atrial Appendage Occlusion Versus Oral Anticoagulation in Atrial Fibrillation

What is the best strategy for preventing stroke in patients with non-valvular AF: anticoagulants or left atrial appendage occlusion (LAAO)? The answer depends on the individual patient’s combination of stroke and bleeding risks. In this study, combined risks favored LAAO for higher bleeding risk, but that benefit became less certain at higher stroke risks.

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