Articles related to ATRIAL FIBRILLATION (AFIB)

Higher moderate-to-vigorous physical activity was associated with lower incident atrial fibrillation risk in a UK Biobank cohort, with a stronger association among participants with atrial cardiomyopathy. The observational design does not establish causality.

Retinal imaging findings were associated with future atrial fibrillation diagnosis in two large UK datasets, with thinning of specific retinal nerve layers observed years before clinical detection. The study identified an early risk signal but did not establish causality or diagnostic utility.

In the randomized DECAF trial, patients undergoing cardioversion who consumed at least one caffeinated coffee daily experienced fewer clinically detected atrial fibrillation recurrences than those abstaining from caffeine. The study was modest in size and further validation is needed.

A randomized crossover trial of 108 habitual cannabis users found fewer premature atrial contractions on cannabis-use days than abstinence days. The short-term physiologic findings provide mechanistic insight but were not designed to evaluate long-term cardiovascular health outcomes.

Among more than 7,300 Swedish patients with Alzheimer’s disease and atrial fibrillation, NOAC use was associated with slower cognitive decline than warfarin or no anticoagulation. The observational findings did not establish causality but suggest potential differences in long-term cognitive outcomes.

In an observational target trial emulation of patients with atrial fibrillation and mitral stenosis, DOACs were associated with higher 1-year stroke risk than warfarin. Bleeding and all-cause mortality risks did not differ between groups.