Articles related to DRUG SAFETY & INTERACTIONS

A study in the Annals of Internal Medicine looked at the association between cardiovascular outcomes and the coprescription of nitrates with PDE5 inhibitors in more than 42,000 men over a 10-year period. Two composite outcomes were measured: 1) cardiac arrest, shock, myocardial infarction, ischemic stroke, or acute coronary arteriography; and 2) syncope, angina pectoris, or drug-related adverse event. The authors found no statistically significant increase in measured cardiovascular AEs.

Published in its entirety in the Journal of the American Geriatrics Society and available here from Guideline Central, the AGS Beers Criteria® also includes a host of resources— from mobile apps to a pocket reference card. The five lists included describe particular medications with evidence suggesting they should be avoided, used in caution, or dosed differently.