American Medical AssociationEffect of Hydroxychloroquine on Clinical Status at 14 Days in Hospitalized Patients With COVID-19

We’ve been hearing about hydroxychloroquine seemingly since the pandemic started, and there is no question that doctors need to determine whether hydroxychloroquine is an efficacious treatment for adults hospitalized with COVID-19. Does this Original Investigation from JAMA finally provide some clarity to the drug’s use among patients hospitalized with the virus?

American College of PhysiciansHydroxychloroquine in Nonhospitalized Adults With Early COVID-19

No effective oral therapy exists for the outpatient treatment of COVID-19. Hydroxychloroquine has in vitro activity against SARS-CoV-2 and has been proposed as a potentially effective treatment. This randomized double-blind, placebo-controlled trial investigated whether hydroxychloroquine could reduce COVID-19 severity in adult outpatients.