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Our understanding of lipid pathology is shifting from what might be called the “LDL hypothesis” to the “atherogenic lipoprotein hypothesis.” LDL is just a surrogate of the actual process of lipoprotein interaction with the arterial wall. This shift in understanding is driving a host of budding therapies with novel approaches to targeting key atherogenesis players like lipoprotein(a) and triglycerides.
Cardiology October 5th 2021
Research shows that the “old” 2015 recommendation would only identify about half of Americans with prediabetes and undiagnosed type 2 diabetes. Based on this data, the US Preventive Services Task Force has lowered the recommended screening age from 40 to 35 years in asymptomatic, nonpregnant adults who are overweight or obese.
Endocrinology, Diabetes, Metabolism August 31st 2021
Pediatric B-cell acute lymphoblastic leukemia (B-ALL) is the most common malignancy seen in children and adolescents and young adults (AYAs). This article highlights two recent studies that provide novel evidence of the association between obesity and increased risk of high-risk B-ALL and the effectiveness of a non-pharmacologic intervention for reducing minimal residual disease (MRD) risk.
Endocrinology, Diabetes, Metabolism June 28th 2021
Journal of Clinical Oncology
An update from the original ASCO guideline on this topic published in 2012, 60 studies, primarily retrospective, were included in the review. New to this version of the guideline, the Panel offers recommendations on approved doses of immunotherapy and targeted therapies that can be offered to obese patients with cancer.
Endocrinology, Diabetes, Metabolism June 21st 2021
Healthgrades for Professionals
Are you biased toward certain types of patients? “Sometimes” is likely your answer, but there are implicit biases that doctors may not be aware they have. To help answer this question, Medscape put together a survey to weigh these biases, with emotional problems coming in at No. 1. Whether they are implicit or explicit, here are the other patient characteristics that commonly trigger a predisposition in doctors.
Allergy & Immunology June 9th 2021
US News & World Report recently published its state healthcare rankings, based on three measures: access to healthcare, quality of care, and overall health of the population, measuring rates of obesity, smoking, suicide, mental health, and mortality for adults and infants. At the top, Hawaii was the clear winner. At the bottom, Mississippi. Where does your state measure up in the rankings?
Allergy & Immunology April 6th 2021