Breast Conservation vs. Mastectomy | Top Health Product Scams | CAR-T for AMLMay 19, 2021 | Oncology Internal Medicine Survival After Breast Conservation vs Mastectomy Adjusted for Comorbidity and Socioeconomic Status In this JAMA Surgery Original Investigation, the researchers fielded a Swedish cohort study of 48,986 women to discover whether breast conservation offers a survival benefit compared with mastectomy when results are adjusted for main confounders such as comorbidity and socioeconomic status. The main outcomes and measures were overall survival (OS) and breast cancer–specific survival (BCSS). Read full article Allergy & Immunology Biggest Waste-of-Money Health Products Being Marketed to Patients From new scams like unproven COVID-19 treatments to the returns-like-a-bad-penny “Diabetes Fast Fixes,” health product swindles are unfortunately part of the world we live in. The too-good-to-be-true claims allure many patients suffering from debilitating conditions, and at best, it may be just a waste of money. At worst, though, some of these products could cause serious problems and possibly even death. Read full article Hematology Universal CAR-T Platform Shows Promising Efficacy in Relapsed/Refractory AML Published in Blood, this article presents initial findings from a proof-of-concept study led by Martin Wermke, MD, from the Technical University of Dresden in Germany. The UniCAR platform uses targeting molecule TM123 and a single-chain variable fragment that is directed against the CD123 antigen, offering a potential new treatment option for patients with relapsed/refractory acute myeloid leukemia (AML). Read full article