Articles related to Neuromusculoskeletal Medicine & OMM

Artri King and other products with a similar name were the subject of an FDA analysis that exposed hidden drug ingredients, including corticosteroids (diclofenac and dexamethasone). The FDA sent warning letters to Amazon, Walmart, and Latin Foods Market on October 28, 2022, for distributing various Artri and/or Ortiga unapproved and misbranded drug products. Some of these products may still be available on the market. These products have already been voluntarily recalled by Walmart and Latin Foods Market.

The knee arthritis meta-analysis reviewed 169 trials involving 21,163 patients, with the evidence demonstrating viscosupplementation is associated with a clinically irrelevant reduction in pain intensity and with an increased risk of serious adverse events compared with placebo. For the meniscus study, the commentary may sum it up best: “Multiple studies, including several with sham surgeries as a control have shown repeatedly over the previous 2 decades that surgery is not superior to physical therapy, yet the issue and use of surgery persist.”

The studies described in Acta Neurologica Belgica assess eight patients who developed a new-onset neuromuscular disorder following COVID-19 vaccination. “These various presentations strengthen the association between COVID-19 vaccination and particular GBS phenotypes,” the researchers noted.

Primary hyperparathyroidism (PHPT) is associated with increased risk for fractures, cardiovascular disease, kidney disease, and cancer, along with increased mortality. In mild PHPT with modest hypercalcemia and without known morbidities, parathyroidectomy is debated because no long-term randomized trials have been performed related to it.

Given the high burden of shoulder conditions, clinicians should pay attention to any factors that may further increase risks. This study found a low incidence of shoulder issues following vaccination in the deltoid muscle but does delineate population at higher risk for developing these issues.

The CDC has released updated guidelines for prescribing opioids. The newest guidelines focus on patient-centered decisions and reduce some limitations on prescribing that were put in place back in 2016. The updated guidance recognizes the ongoing increase in opioid-related deaths, but seeks to give physicians and patients more direction in managing individual therapy.