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The New England Journal of Medicine
In the US, only two emergency contraceptive methods have been FDA approved: oral levonorgestrel and oral ulipristal acetate. However, the copper IUD appears to be an order of magnitude more effective than the approved methods and so copper IUD is often used. But women prefer the levonorgestrel IUD. This study looked to compare the two IUDs as emergency contraceptives. Among 711 women randomized to copper versus levonorgestrel IUDs, pregnancy rates were 1 in 317 in the levonorgestrel group and 0 in 321, equating to non-inferiority for the levonorgestrel IUD.
Emergency Medicine December 21st 2022
Hematology, ASH Education Program
Today, it is possible to safely treat CML throughout pregnancy with little danger to the unborn child, as TKIs can now be safely administered during the later stages of pregnancy, according to new research. After beginning or continuing TKI therapy, a sizable majority of patients can be managed by observation alone, and disease control can be attained. IFN-α may be given in any trimester with little harm to the fetus if active treatment is necessary. Most essential, however, is a multidisciplinary strategy to offer clear and concise guidance to enable both the mother and the family to participate in the decision-making process.
Hematology December 19th 2022
MDLinx
In an analysis of electronic messages from patients, women physicians, DOs, and PCPs are twice as likely as other physicians to be referred to by their first name instead of as “doctor.” Is it acceptable? Is it good for the relationship? What are the best responses for institutions and individual practitioners?
Family Medicine/General Practice December 13th 2022
ACP Internist
After 5 years of denosumab therapy, this patient has had no fractures and bone density scores have improved. You plan to discontinue denosumab. What else should be done?
Family Medicine/General Practice December 7th 2022
In this cohort study of insurance data over an 18-year period covering more than 15,000 pregnancies that involved methadone or buprenoprine use, buprenorphine in pregnancy was associated with a lower risk of adverse neonatal outcomes versus methadone use. However, the risk of adverse maternal outcomes was similar.
Internal Medicine December 6th 2022
Healthgrades for Professionals
These specialties had the highest proportion of doctors still making student loan payments, per the 2022 Medscape report: Emergency Medicine (31%) Physical Medicine & Rehabilitation (31%) Pediatrics (31%) Neurology (28%) Otolaryngology (28%) Family Medicine (28%) For the least debt-burdened: Pulmonary Medicine (10%) Public Health & Preventive Medicine (11%) Rheumatology (12%) Diabetes & Endocrinology (15%) Dermatology (16%) Cardiology (16%)
Allergy & Immunology December 5th 2022