Articles related to Obstetrics & Gynecology

A gynecologic oncologist reviews the current role of immune checkpoint inhibition across locally advanced and recurrent cervical cancer settings, including KEYNOTE-A18 survival data, key regulatory distinctions, and unanswered sequencing questions.

A jury assigned 35% of liability to a second-opinion physician and health center after a patient underwent an unnecessary hysterectomy based on a contaminated biopsy specimen, finding that discordant pathology results were not reconciled and informed consent was not obtained.

An ESMO express update to epithelial ovarian cancer guidelines added rucaparib and mirvetuximab soravtansine as treatment options, but expert commentary and two subsequent FDA approvals have raised questions about the update’s current clinical applicability.

Hematopoietic loss of the X chromosome in peripheral blood was associated with more than twofold the odds of failing to conceive naturally in a Japanese multicenter case-control study, with no corresponding association found in women undergoing ART.

A 14-year international consensus effort involving 56 professional and patient organizations has renamed polycystic ovary syndrome to polyendocrine metabolic ovarian syndrome, a shift designed to better reflect the condition’s systemic hormonal and metabolic pathophysiology.

Among 206,464 mother-child pairs, children of mothers with stably optimal glycemic management after a GDM diagnosis had obesity risk at age 10 nearly identical to children unexposed to GDM. Children of mothers with suboptimal trajectories had a 62% higher risk.