Articles related to Obstetrics & Gynecology

In a Norwegian cohort of more than 200,000 children, maternal COVID-19 during pregnancy was not associated with higher overall rates of childhood neurologic or neurodevelopmental disorders, although follow-up remained relatively short.

A rare case of anti-ER5-mediated hemolytic disease of the fetus and newborn required international sourcing of ultrarare blood products and multiple intrauterine transfusions, highlighting the complexity of managing alloimmunization involving newly recognized high-incidence red blood cell antigens.

Analysis of postmenopausal ovarian tissue from 28 women found that ovaries continue to undergo molecular remodeling decades after menopause, with age-related increases in inflammatory and tissue-remodeling pathways that overlap with biologic processes observed in ovarian cancer.

Women with bulimia nervosa demonstrated smaller total cortical surface area and reduced nucleus accumbens volume compared with healthy controls in a large international neuroimaging study, with more frequent binge-eating episodes associated with additional structural differences across brain regions involved in reward, cognitive control, and interoception.

First-trimester benzodiazepine exposure was not associated with a meaningful increase in major congenital malformations in a large US cohort study, although findings related to coexposure with other psychoactive medications remained inconsistent and require further investigation.

Across three cohorts, molecular patterns in human milk were associated with maternal nutritional status, mammary biological signatures, and infant growth. Seven candidate biomarkers emerged, but their clinical utility and the proposed vitamin B5 mechanism remain unproven.