Articles related to Pulmonology

Thinking of starting the new year off with a diet? According to U.S. News and World Report, the Mediterranean diet is the best overall diet for adults. The diet was ranked first in the categories of best diets for healthy eating, easiest diets to follow, and best diets for diabetes, among other measurable categories.

A “breakthrough therapy” designation has been granted by the FDA to CLN-081 for the treatment of a subset of non-small cell lung cancer. The designation applies to use of the agent by patients with locally advanced or metastatic EGFR-mutated NSCLC who previously received chemotherapy and comes as a phase 1/phase 2a clinical trial is underway.

A systematic review identified 204 eligible publications from 2000 through 2017, with much of the evidence consisting of systematic reviews of observational data, consensus guidelines, case series, and case reports. Due to the paucity of high-quality evidence on management of immune-related adverse events, recommendations are based on expert consensus.

In this clinical trial, the authors attempt to answer the question of whether a high-intensity interval training program can improve cardiorespiratory fitness and delay the biochemical progression of prostate cancer in patients who are undergoing active surveillance. One group was asked to complete 12 weeks of thrice-weekly, supervised aerobic sessions on a treadmill at 85% to 95% of peak oxygen consumption (V̇o2). The usual care group maintained their normal exercise levels.

The encouraging results of the phase 3 ORIENT-11 trial, which included 397 patients with previously untreated, locally advanced metastatic non-squamous NSCLC without sensitizing EGFR or ALK aberrations, were published in the Journal of Thoracic Oncology.

From the American Red Cross to volunteering overseas, there are plenty of feel-good “enlistments” out there for the practicing or retired physician, which can help ward off boredom and burnout while adding the benefit of perhaps learning a new skill or meeting new people. Whether your goals are short-term or you’re in for the long haul, here are nine opportunities to help humanity and feel good about the part you’re playing in the world.