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This Annals of Internal Medicine study reports an 82% decreased risk for reinfection for those previously infected and then vaccinated, versus those previously infected but who remained unvaccinated. Reinfection in both groups was relatively rare.

Similarly, can you determine how to treat a 22-year-old man with Marfan syndrome who complains of an asymptomatic rash on his arms and neck that began over a year ago? Take the quiz to test your diagnostic prowess.

Can you determine the appropriate case management for a 68-year-old man who is evaluated for an episode of syncope and repeated episodes of near-fainting when standing and working on his tractor? On physical examination, vital signs are normal. Supine blood pressure is 124/78 mm Hg, and pulse rate is 76/min. After the patient stands for three minutes, standing blood pressure is 88/68 mm Hg, and pulse rate is 94/min. The remainder of the examination is normal. How would you proceed?

The CDC has released updated guidelines for prescribing opioids. The newest guidelines focus on patient-centered decisions and reduce some limitations on prescribing that were put in place back in 2016. The updated guidance recognizes the ongoing increase in opioid-related deaths, but seeks to give physicians and patients more direction in managing individual therapy.

A 56-year-old man has had right-upper-quadrant abdominal pain for several months but is otherwise healthy. He does not drink alcohol, has not been exposed to other hepatotoxins, and takes no medications. On physical examination, vital signs are normal. Abdominal examination reveals hepatosplenomegaly. The remainder of the physical exam is normal. What would you do?

A new cohort study has found physical, mental, and cognitive symptoms in patients one year after being treated in an intensive care unit (ICU) for COVID-19. The study involved an exploratory multicenter prospective cohort study that included 246 patients who were alive one year following ICU treatment for COVID-19. Three-quarters of patients reported physical symptoms, 1/4 reported mental symptoms, and about 15% reported cognitive symptoms a year after being hospitalized with the respiratory illness.