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Psychiatrist.comComparative Effectiveness of Intravenous Ketamine and Intranasal Esketamine in Clinical Practice Among Patients with Treatment-Refractory Depression: An Observational Study

This observational study compared IV ketamine (47) to IN esketamine (15) in 62 adults suffering treatment-resistant depression. Response was measured using the QIDS-SR tool. The results? The two formulations were comparable in terms of change between baseline and endpoint QIDS-SR and response rates. However, IV ketamine generated benefits with fewer treatments.

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