Magnesium supplementation has been linked to small blood pressure reductions in some studies, particularly among magnesium-deficient individuals. Overall evidence remains mixed.
Editorial Note: Evidence on magnesium supplementation shows mixed and modest effects on blood pressure. Findings do not support magnesium as a treatment for hypertension and should be considered adjunctive only.
Clinical Considerations
- Average BP changes are small and inconsistent.
- Greater impact is seen in deficiency states.
- No trials link supplementation to outcomes.
- Interaction-related hypotension can occur.
Practice Applications
- Frame magnesium as adjunctive, not therapeutic.
- Reinforce guideline-based hypertension care.
- Monitor for drug interactions and symptoms.
- Encourage supervised use only.
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