Articles related to BIPOLAR DISORDER

How do you decide between different atypicals for a patient who’s never been on an atypical before? What about carbamazepine and oxcarbazepine for bipolar disorder? Gregory Mattingly, MD, provides practical guidance on these questions posed at the Psych Congress Regional meeting.

In a study of more than 22,000 patients with schizophrenia, schizoaffective disorder, or bipolar disorder, 24% also had obsessive-compulsive symptoms; 12% had a diagnosis of OCD. Both co-morbidities were associated with higher rates of aggressive behavior, cognitive problems, and hallucinations or delusions.

In this interview with Dr. Wendy Marsh, director of the Bipolar Disorders and Depression Specialty Clinics at the University of Massachusetts Chan Medical School, she discusses how treatment can better address quality-of-life issues for individuals with bipolar depression.

The association between lithium use and chronic kidney disease (CKD) has been unclear. This study showed that lithium over the long-term (i.e., 10 years) accelerated the decline in eGFR attributed to aging.

Rakesh Jain, MD, MPH, a member of the steering committee for the Psych Congress, and co-authors Huy-Binh Nguyen, PhD, and Mousam Parikh, both of AbbVie, respond to inquiries regarding their study, which discovered a discrepancy between treatment recommendations and the prescription habits of clinicians treating bipolar disorder. The study’s motivation, the most important findings, and suggestions for doctors treating bipolar disorder who want to follow the most recent treatment recommendations are covered in Part 1 of this Q&A.

The author concludes that “careful use of T3  and L-T4  can be critical mood-stabilizingoptions, especially for depressive illness that has not responded to first-line therapies,and can provide an alternative to other augmentation strategies such as atypicalantipsychotics, lithium, or esketamine/ketamine.”