Articles related to BIPOLAR DISORDER

The association between lithium use and chronic kidney disease (CKD) has been unclear. This study showed that lithium over the long-term (i.e., 10 years) accelerated the decline in eGFR attributed to aging.

Rakesh Jain, MD, MPH, a member of the steering committee for the Psych Congress, and co-authors Huy-Binh Nguyen, PhD, and Mousam Parikh, both of AbbVie, respond to inquiries regarding their study, which discovered a discrepancy between treatment recommendations and the prescription habits of clinicians treating bipolar disorder. The study’s motivation, the most important findings, and suggestions for doctors treating bipolar disorder who want to follow the most recent treatment recommendations are covered in Part 1 of this Q&A.

The author concludes that “careful use of T3  and L-T4  can be critical mood-stabilizingoptions, especially for depressive illness that has not responded to first-line therapies,and can provide an alternative to other augmentation strategies such as atypicalantipsychotics, lithium, or esketamine/ketamine.”

The potential link between insulin resistance and bipolar disorder is causing a “paradigm shift in psychiatry,” remarked Dr. Cynthia Calkinan, associate professor of psychiatry at Dalhousie University in Halifax, Nova Scotia, Canada.

Anxiety disorders are among the most common of psychiatric disorders, with estimates suggesting a lifetime prevalence in the US of approximately 32%. But development of new and effective treatments for anxiety disorders has lagged behind new treatments for other conditions such as major depressive disorder, bipolar disorder, and schizophrenia. This article reviews current treatment and their effectiveness, and highlights the emerging new hopefuls.

In this cross-sectional study of 586 probands and 698 first-degree relatives, cannabis use disorder and bipolar disorder II in probands were associated with an independent increase in risk of cannabis use disorder in relatives; bipolar disorder I and major depressive disorder in probands were not significantly associated with cannabis use disorder in relatives. The risk of cannabis use disorder was highest among relatives with both familial and individual history of bipolar disorder II.