Articles related to CLINICAL TRIALS

This study underscores the critical need for precise diagnostic criteria in treating unexplained strokes and the potential reevaluation of anticoagulant use in patients with atrial cardiopathy, opening new avenues for research and patient care.

Lamotrigine stands out for its efficacy in preventing depressive episodes in bipolar I disorder, offering a nuanced option for mood stabilization with an antidepressant emphasis. Understanding its specific clinical applications can enhance treatment strategies for mood disorders.

Recent findings from the ASCO Gastrointestinal Cancers Symposium 2024 underscore the potential of innovative therapeutic combinations in enhancing outcomes for hepatocellular carcinoma patients, particularly those with unresectable or high-risk disease.

In the landmark KEYNOTE-564 trial, pembrolizumab has emerged as a pivotal advancement in kidney cancer treatment, offering hope by significantly prolonging survival in patients with high-risk ccRCC post-nephrectomy.

In a phase 3 study, iloperidone demonstrated a significant improvement in treating bipolar mania, marked by a reduction in the Young Mania Rating Scale (YMRS) scores.

In the phase 3 GETUG-AFU 18 trial, high-dose radiotherapy (80 Gy) combined with long-term androgen deprivation therapy markedly improved 10-year progression-free and overall survival in high-risk prostate cancer patients, without additional toxicity.