Articles related to CLINICAL TRIALS

In a recent study, 91% of patients with transfusion-dependent β-thalassemia achieved independence from transfusions following treatment with Exagamglogene Autotemcel.

In patients with type 2 diabetes and stage 5 chronic kidney disease, the use of SGLT2 inhibitors is associated with a lower risk of initiating dialysis and experiencing major cardiovascular events, providing a promising therapeutic avenue in a population at elevated risk.

This phase 2 study underscores the challenges in enhancing therapeutic outcomes in metastatic castration-resistant prostate cancer with AZD4635 combined with immunotherapy, indicating a minimal PSA response among treated patients.

In the recent phase 3 trial, recombinant ADAMTS13 demonstrated a profound capability to maintain ADAMTS13 activity at approximately 100% of normal levels, highlighting its potential to substantially reduce thrombotic complications in patients with congenital TTP.

In a controlled trial conducted over a six-month period in Mali, subcutaneous administration of the monoclonal antibody L9LS to children aged 6 to 10 achieved an efficacy rate of up to 77% in preventing clinical malaria.

In a randomized trial involving over 500 preterm infants, researchers found that neither specialized amino acid solutions nor milk supplements significantly altered body composition at 4 months, suggesting that simpler feeding regimes may be equally effective.