By 2018, gabapentin and opioids were prescribed in an overlapping manner in 7.6% of prescriptions. Prescribers are likely responding to restrictions on opioid prescribing put in place during the opioid epidemic. Increased co-prescribing was most frequently done under the direction of a pain specialist. Still, the effectiveness of the concurrent prescribing of opioids and gabapentin is uncertain and potentially dangerous because of an association with all-cause and drug-related hospitalizations.

This physician relates his struggle with drinking that was mostly “internal, with few external consequences” as he puts it — just a few occasional red lights as he looked at how his alcohol use was touching his relationships with himself, his wife, and his kids.

Genetic tools such as CRISPR could enable creating a close approximation Neanderthal or other lost species DNA. Harvard geneticist George Church, PhD, argued some potential benefits to humans. But what are the potential implications and how should the question be weighed?

After earning a doctorate in nursing practice, this NP began to refer to herself as “Doctor Sarah Erny.” Now she must pay a civil fine and clean up her attribution.

Data from Study 2102-HEM-101, an open-label, single-arm, multicenter phase 1/2 trial, were used to support the approval. The Abbott RealTime IDH1 Assay was used to identify 147 adults with relapsed or refractory AML who had an IHD1 mutation. Olutasidenib treatment resulted in a 35% complete remission (CR) or complete remission with partial hematologic recovery in patients (CRh).

In this multi-institutional study, AT significantly increased progression-free and overall survival in 430 patients with node-negative (N0) disease after NAT for localized pancreatic cancer (4.1 vs 2.1 and 5.3 vs 3.5 years, respectively). Patients who received neoadjuvant radiation had their overall survival benefit scaled back, while patients with perineural invasion saw an increase.