Publication: The LancetDesign: Open-label, single-arm study of 157 patients who had undergone a median of six previous lines of therapy and who received at least one dose of teclistamab; 40 patients received the recommended phase II dose of teclistamabResults: Of the 40 receiving the phase II dose, 58% achieved a very good partial response or better; 40% achieved a complete response or better

About 75% to 80% of children with pediatric AML have clonal, acquired, somatic cytogenetic abnormalities (CAs) detected. Hematology Advisor briefs the information originally appearing in Genes, which reviews the current knowledge on evaluating pediatric patients based on cytogenetics and molecular subtypes to help match patients to risk-adapted therapies.

Publication: Blood AdvancesStudy Design: Prospective study with unmatched health care workforce control group, receiving either Moderna or Pfizer COVID vaccination.Study Population: 23 patients with CLL (61%), lymphoma (39%) (including DLBCL), MCL (13%) and 4% with less common lymphomas.Outcome: Lymphoma patients had significantly lower anti-S IgG titers 28 days post-vaccination compared with controls. Related Article: Efficacy of the BNT162b2 mRNA COVID-19 Vaccine in Patients with B-Cell Non-Hodgkin Lymphoma

A discussion between an oncologist and a patient, Evelyn, a transgender woman with prostate cancer who was able to change the doctor’s binary view of gender thanks to a candid conversation and the help from a dozen eggs – brown and blue.

An OBGYN voices frustration — “silently cursing behind my mask” – with the patients who “recite a litany of scientifically illiterate reasons for not taking” the COVID-19 vaccine despite its 99%+ effectiveness in keeping them alive. Do you share this doctor’s sentiments?

Research shows that the “old” 2015 recommendation would only identify about half of Americans with prediabetes and undiagnosed type 2 diabetes. Based on this data, the US Preventive Services Task Force has lowered the recommended screening age from 40 to 35 years in asymptomatic, nonpregnant adults who are overweight or obese.