Articles related to Clinical Pharmacology

Pharmacogenomics (PGx) researches how germline (or inherited) alterations impact a person’s receptivity to medication. Almost everyone has a clinically significant variant of one or more pharmacogenes. Genetic variations in PK, PD, and HLA are linked to variations in drug response. Evidence only supports the utility of PGx testing for the four genes CYP2C19, CYP2D6, HLA-B15:02, and HLA-A31:01 in mental health. Fill out the CPE exam and submit it online at www.pharmacist.com/education if you’re interested in receiving 1 hour of CPE credit for this activity.

In the US, the use of biosimilars is becoming more and more important because of the potential for cost savings to increase patient access to biologic medicines and lower total healthcare expenditures. Healthcare professionals and patients have been the subjects of surveys on biosimilars, but recent comprehensive quantitative data about US pharmacists’ attitudes toward and comprehension of biosimilars are scarce. The majority of US pharmacists understood the fundamental ideas behind biosimilar drugs; however, certain knowledge gaps were concentrated in the areas of interchangeability and substitution. Only slightly more than half of those surveyed said they felt confident answering patients’ inquiries about biosimilars. To bridge these gaps and boost confidence in administering biosimilars, US pharmacists need additional and targeted instructional techniques.

Anti-Xa levels could be helpful for determining current medication concentrations, determining the immediate safety of therapy, and providing direction for potential clinical actions. Further study is needed to determine how dose titration and reversal therapy based on anti-Xa level results in significant bleeding.

Akorn previously manufactured a long list of generic drugs, including orals, injectables, and topicals for a wide range of indications, from antivirals and antibiotics to ophthalmic agents, asthma medications, and analgesics. Some of these agents have other manufacturers, but Akorn was either the sole supplier or had a very large market share for others.

For the first time, Uber Health users, including healthcare providers and health plans, will be able to manage prescription delivery from any pharmacy in their service area via the same platform they use to coordinate patient transportation. This launch allows providers to offer a comprehensive suite of care solutions that extend beyond the four walls of a clinic and is intended to improve patient experiences and health outcomes.

This activity aims to educate the multidisciplinary care team treating pediatric ADHD, including psychiatrists, pediatricians, PCPs, pharmacists, and dietitians/nutritionists. After completion, participants will be better able to describe the role of dietary deficiencies of essential fatty acids (EFAs) and genetic variants of metabolism in the pathophysiology of ADHD; review the most recent data on the safety and efficacy of supplementation with EFAs for ADHD management in children and adolescents; differentiate dietary supplements from medical foods; and create personalized nutritional therapy plans for ADHD patients by considering the individual needs of each patient and the differences among available dietary products.