Articles related to Endocrinology, Diabetes, Metabolism

Publication: JAMA Oncology Objective: With NSCLC having relatively poor outcomes and the significant data supporting the use of metformin as an antineoplastic agent, the researchers wanted to compare overall or progression-free survival in chemoradiation alone vs. chemoradiation + metformin stage III NSCLC patients. Design: Randomized clinical trial, open-label, phase 2 study; 167 eligible patients

Findings: Primary outcomes included AMI, HF, stroke, and CVEs; 51 secondary and safety outcomes included angioedema, cough, syncope, and electrolyte abnormalities. ACE inhibitors were associated with a significantly increased risk of four secondary and safety outcomes compared with ARBs.Design: Multinational cohort study; Patients: ~2.3M ACE, ~674K ARB 

According to the interim guidance, “remote-learning highlighted inequities in education, was detrimental to the educational attainment of students of all ages, and exacerbated the mental health crisis among children and adolescents.” The AAP continues to recommend that all staff and students who are 2 years or older wear face masks unless medical or developmental conditions prohibit their use, urging everyone who is eligible to get vaccinated against COVID-19.

According to a study of 135,000 doctors by Doximity, male physicians made, on average, 28% more than females in 2020, a 3% increase from the 2019 numbers. The survey, along with Medscape’s poll in 2021 that showed male specialist physicians overall making 33% more than females, points to a few other large gender pay gaps, as well as some in which women doctors make salaries closer to those of men.

Medical jargon and the complexity of medical information may cause misunderstandings and patient discomfort when bedside case presentations are taking place. To see if outside-the-room case presentations were more effective, the researchers examined the patients’ average knowledge of three dimensions of their medical care in both settings — understanding their disease, the therapeutic approach being used, and further plans for care.

There are several reasons why the COVID-19 Delta variant – responsible for the COVID crisis in India – has public health experts and doctors concerned, including its transmissibility and disease severity. You likely already know the Delta “variant of concern” is more contagious than previous variants (denoted by the Greek alphabet), but here are five other important details you should be aware of.