Articles related to Hematology

Valoctocogene roxaparvovec gene therapy demonstrates long-term efficacy in reducing bleeding episodes and factor VIII use in patients with severe hemophilia A, potentially changing the treatment landscape for this condition.

AL amyloidosis can present with distinctive periorbital signs, including petechiae and waxy eyelid papules, which may worsen with trauma.

In a phase 2 study of nipocalimab for early-onset severe hemolytic disease of the fetus and newborn, 54% of high-risk pregnancies resulted in live births at or after 32 weeks’ gestation without intrauterine transfusions, compared to a historical benchmark of 0%.

AL amyloidosis, a rare disease with an estimated global incidence of 10 cases per million population, can present with various symptoms depending on organ involvement, making early diagnosis challenging but crucial for effective treatment.

Vitamin B12 deficiency manifests in four critical ways: anemia, nerve damage, birth defects, and DNA damage. Recognizing these key symptoms and understanding their underlying mechanisms is essential for timely diagnosis and effective treatment, potentially preventing severe long-term health consequences.

Blood thinners interact with various medications and supplements, potentially increasing bleeding risk or reducing efficacy. Physicians should be aware of these interactions and educate patients on the importance of consulting healthcare professionals before taking new products.