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Clinical Advances in Hematology & OncologyHyper-CVAD–Based Regimens in Adult Patients with Acute Lymphoblastic Leukemia

The hyperfractionated cyclophosphamide, vincristine, doxorubicin, and dexamethasone
(hyper-CVAD) regimen has undergone many modifications to make administration more palatable and user-friendly for patients and physicians in community and academic settings, including refinements to avoid complications and reduce adverse events. Dr. Elias Jabbour of MD Anderson Cancer Center reviews a number of these modifications in this interview.