Journal of VisionSpatiotemporal Summation of Perimetric Stimuli in Healthy Observers

The article proposes a computational model to account for the complex interaction between stimulus size, duration, and retinal cones-to-retinal ganglion cells ratio. The findings challenge the assumption of a constant critical number of retinal ganglion cells with respect to the enlargement of the critical area of summation with eccentricity in the macula, proposing instead a constant critical total retinal input. The research has implications for understanding perimetric sensitivity and modeling disease, particularly glaucoma.