Articles related to ADDICTION MEDICINE

Gabapentin has been increasingly used as part of a multimodal analgesia regimen to reduce opioid use in perioperative pain management. In this cohort study of 237,872 adults aged 65 years or older, perioperative gabapentin users had significantly increased risk of delirium, new antipsychotic use, and pneumonia compared with nonusers after major surgery.

The colorful fentanyl, known as “rainbow fentanyl,” has been identified in 18 different states and has been found in a variety of forms, including pills, powder, and blocks that resemble sidewalk chalk, according to a press release from the agency. No particular color has been found to have a higher potency through testing. According to the DEA, every shade, shape, and size should be viewed as being exceedingly harmful.

The recent United States Supreme Court ruling raises the bar for evidence that must be shown by the government in order to successfully prosecute doctors who prescribe excessive dosages of painkillers — a huge win for prescribers.

Sufentanil sublingual tablet 30 mcg (Dsuvia, AcelRx), an effective novel tablet formulation of the synthetic opioid sufentanil, has been given FDA approval for the management of severe acute pain in adult patients in licensed medically supervised healthcare settings. The medication is administered sublingually in a single-dose, prefilled applicator.

In this double-blind randomized clinical trial with 93 participants, the percentage of heavy drinking days during 32 weeks of follow-up was significantly lower in the psilocybin group than in the diphenhydramine group and was accompanied by a decrease in daily alcohol consumption.

The results of this study provide evidence that genetically predicted global cortical thickness (GCT) wasassociated with alcoholic drinks consumed per week and binge drinking frequency afteraccounting for neuropsychiatric phenotypes, substance use, trauma, andneurodegeneration.