Articles related to BIRTH DEFECTS
Timing of Primary Surgery for Cleft Palate
This study offers valuable insights into the optimal timing for cleft palate surgery in infants, showing a lower risk of velopharyngeal insufficiency when surgery is performed at 6 months. Consider this data when planning surgical interventions and advising parents.
Otolaryngology September 7th 2023
Atomoxetine in Early Pregnancy and the Prevalence of Major Congenital Malformations: A Multinational Study
Although research exists on the impact of CNS stimulants used in pregnancy, only a few small studies have looked at atomoxetine and pregnancy outcomes. This large cohort study of 4.2 million pregnancies ending in live births in northern Europe and the US reviewed nearly 1,000 pregnancies exposed to atomoxetine in the first trimester. Compared with non-exposed pregnancies, there was no observed increase in major congenital abnormalities with atomoxetine use in the first trimester.
Internal Medicine January 18th 2023
Preconception Antidiabetic Drugs in Men and Birth Defects in Offspring
Diabetes medications, such as metformin, have glucose-independent effects on the male reproductive system. However, until now, it was unknown if these effects lead to birth defects in offspring. This study concludes that metformin intake in men is associated with major birth defects, particularly genital birth defects in boys.
Endocrinology, Diabetes, Metabolism April 5th 2022