Articles related to CLINICAL RESEARCH

Researchers from Texas Tech University discovered that participants who had only ever sent (but never received) sexts reported higher levels of depression, anxiety, and sleep problems than the other groups. They also suggested a link between sexting, marijuana use, and compulsive sexual behavior. According to the report, more than half of adults have sent a sext, and women are up to four times more likely than men to have received nonconsensual sexts. Many people say they enjoy consensual sexting because it empowers them and builds their self-confidence, but nonconsensual sexting can cause feelings of violation and awkwardness.

Some cans of Bumble Bee, Chicken of the Sea, StarKist, Safe Catch, and Wild Planet tuna contained higher than usual mercury levels, despite the average level being within standards.

Researchers examined the OTC drug shopping patterns of 153 women before being diagnosed with ovarian cancer and compared them to the patterns seen in 120 women without ovarian cancer. Participants in the study also answered questions regarding the symptoms they had and the number of times they had seen their general practitioner in the year preceding a cancer referral or diagnosis. Eight months before diagnosis, there was a substantial difference in the OTC drug buying habits of women with and without ovarian cancer. Up to nine months prior to diagnosis, there was a rise in the purchasing of dyspepsia medications.

The analysis found similar benefits for most nonpharmacologic treatments and antidepressants as first-step treatments in MDD. As 1st-line therapy, cognitive behavioral therapies (CBTs) were similar in response to second-generation antidepressants (SGAs) in terms of benefit and remission rates, but discontinuation for adverse events was higher with SGAs. The complementary and alternative medicine interventions St. Johns Wart and acupuncture were also similar to SGAs in terms of response and remission. However, the combination of acupuncture and SGAs yielded higher remission rates. Exercise was also similar to SGAs in remission rates; adding exercise to SGAs gave no added benefit. Antidepressants had a higher risk of discontinuation because of adverse events. For second-step therapies, different switching and augmentation strategies provided similar symptomatic relief.

In an analysis of 26 reviews covering 8 antidepressant classes and 22 pain conditions, no review provided a high level of evidence for the effectiveness of antidepressants for chronic pain. The strongest evidence may be for SNRIs for back pain, postoperative pain, neuropathic pain, and fibromyalgia.

In an analysis of 19 studies across 12 countries involving more than 25,000 participants, individuals in highest 20% bracket for omega 3 levels had 13% less risk for developing CKD compared with participants in the lowest 20% bracket. Results were consistent and independent of subgroup variables of age, GFR, hypertension, CAD, and diabetes.