Articles related to CLINICAL STUDY

This prospective cohort study measured cardiac arrhythmias in patients with chronic drug-resistant epilepsy. Using subcutaneous cardiac monitors programmed to record episodes of tachycardia, bradycardia, or asystole ≥3 seconds, 90% of study patients had episodes of sustained tachycardia, 25% had bradycardia and nearly 10% had asystole.

Researchers used retinal imaging to examine the eyes of 200 people with age-related macular degeneration (AMD) to see who had subretinal drusenoid deposits (SDDs). Patients were asked to fill out a questionnaire about their family history of cardiovascular disease. There were 97 SDDs and 103 drusen only among the 200 patients. 47 of the 200 patients had severe heart disease, and 40 of the 47 (86%) had SDDs. In comparison, 57 (43%) of the 153 AMD patients who did not have these severe diseases had SDDs. According to the researchers, AMD patients who had these severe cardiovascular diseases and strokes were nine times more likely to have SDDs than those who did not.

In a study of 844,000 children and adolescents without prior COVID infection, vaccine effectiveness was approximately 61% in children and 67% in adolescents versus the delta variant, but only approximately 16% and 26%, respectively, versus omicron.

Some experts responded to the recently published study, stating that “These authors have been pushing back against treating COVID as airborne for 3 years,” and that the study “will be used to justify policies of supplying healthcare workers … with inadequate protection.”

The master cell growth regulator mTORC1 is known to be hyperactive in colon cancer. This study shows that in mice, a low protein diet blocked mTORC1’s nutrient signaling pathway, stopping the cancer from growing and leading to increased cancer cell death.

Versus placebo, pemafibrate yielded a more than 25% greater reduction in triglycerides, VLDL, remnant cholesterol, and apolipoprotein C-III in patients with type 2 diabetes. However, there was no reduction versus placebo in MI, ischemic stroke, need for coronary revascularization, or CV death.