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Psychiatrist.com
Although research exists on the impact of CNS stimulants used in pregnancy, only a few small studies have looked at atomoxetine and pregnancy outcomes. This large cohort study of 4.2 million pregnancies ending in live births in northern Europe and the US reviewed nearly 1,000 pregnancies exposed to atomoxetine in the first trimester. Compared with non-exposed pregnancies, there was no observed increase in major congenital abnormalities with atomoxetine use in the first trimester.
Internal Medicine January 18th 2023
The New England Journal of Medicine
In the US, only two emergency contraceptive methods have been FDA approved: oral levonorgestrel and oral ulipristal acetate. However, the copper IUD appears to be an order of magnitude more effective than the approved methods and so copper IUD is often used. But women prefer the levonorgestrel IUD. This study looked to compare the two IUDs as emergency contraceptives. Among 711 women randomized to copper versus levonorgestrel IUDs, pregnancy rates were 1 in 317 in the levonorgestrel group and 0 in 321, equating to non-inferiority for the levonorgestrel IUD.
Emergency Medicine December 21st 2022
Hematology, ASH Education Program
Today, it is possible to safely treat CML throughout pregnancy with little danger to the unborn child, as TKIs can now be safely administered during the later stages of pregnancy, according to new research. After beginning or continuing TKI therapy, a sizable majority of patients can be managed by observation alone, and disease control can be attained. IFN-α may be given in any trimester with little harm to the fetus if active treatment is necessary. Most essential, however, is a multidisciplinary strategy to offer clear and concise guidance to enable both the mother and the family to participate in the decision-making process.
Hematology December 19th 2022
Modern Optometry
During pregnancy and the postpartum period, the body is subjected to abnormal stress, raising the possibility of eye and vision-related conditions and complications. Refractive changes, central serous chorioretinopathy, Purtscher-like retinopathy, diabetes, hypertension, and immunologic diseases are examples of eye and vision-related conditions and complications. Although diabetic retinopathy that develops during pregnancy usually resolves on its own after delivery, women are still at risk of progression for up to a year after delivery.
Ophthalmology December 12th 2022
In this cohort study of insurance data over an 18-year period covering more than 15,000 pregnancies that involved methadone or buprenoprine use, buprenorphine in pregnancy was associated with a lower risk of adverse neonatal outcomes versus methadone use. However, the risk of adverse maternal outcomes was similar.
Internal Medicine December 6th 2022
MedPage Today
For moms with highest levels of morning caffeine intake, at age 7-8 their children were about ½ to 1 inch shorter compared with mothers with no or lower caffeine intake.
Family Medicine/General Practice November 16th 2022