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British Medical Journal (The BMJ)
A national case-control study of 108,366 women found that prolonged use of injectable medroxyprogesterone acetate was associated with a 5.55-fold increased risk of intracranial meningioma requiring surgery (95% CI 2.27-13.56), while levonorgestrel IUDs showed no increased risk.
Obstetrics & Gynecology November 26th 2024
The New England Journal of Medicine
Sexual dysfunction negatively affects mental health, vitality, and social functioning, with an impact on quality of life comparable to chronic back pain or diabetes.
Endocrinology, Diabetes, Metabolism September 4th 2024
In a phase 3 trial involving 103 pediatric patients with congenital adrenal hyperplasia, crinecerfont treatment resulted in a mean reduction of androstenedione levels by 197 ng/dL after 4 weeks, compared to an increase of 71 ng/dL in the placebo group.
Endocrinology, Diabetes, Metabolism August 21st 2024
Epoch Health
Early ovary removal may lead to abrupt endocrine dysfunction, potentially increasing the risk of cognitive impairment and dementia in women.
Endocrinology, Diabetes, Metabolism July 29th 2024
MDLinx
Oxytocin nasal spray shows promise as an adjunct therapy for acute loneliness, potentially improving patient engagement in the initial phases of psychotherapy.
Psychiatry July 17th 2024
Cleveland Clinic Journal of Medicine
This case study details the diagnostic process of a young male with hypokalemia and metabolic alkalosis, culminating in the identification of an ectopic ACTH-producing pulmonary carcinoid tumor.
Endocrinology, Diabetes, Metabolism July 3rd 2024