Articles related to PEDIATRIC ENDOCRINOLOGY

Current evidence indicates positive mental health outcomes with gender-affirming care, with studies showing decreased rates of depression, self-harm, and suicidal ideation among treated adolescents.

In a phase 3 trial involving 103 pediatric patients with congenital adrenal hyperplasia, crinecerfont treatment resulted in a mean reduction of androstenedione levels by 197 ng/dL after 4 weeks, compared to an increase of 71 ng/dL in the placebo group.

A recent study shows that combining meal replacement therapy with financial incentives led to a 6 percentage point greater reduction in BMI for adolescents with severe obesity compared to meal replacement therapy alone.

Genetic variants in the vitamin D pathway can lead to idiopathic infantile hypercalcemia, with CYP24A1 mutations being the most common cause.