Articles related to PEDIATRIC ENDOCRINOLOGY

The presence of hypophosphatemic rickets with elevated FGF23 levels in conjunction with classical features provides crucial diagnostic insights for clinicians evaluating pediatric bone disorders.

Current evidence indicates positive mental health outcomes with gender-affirming care, with studies showing decreased rates of depression, self-harm, and suicidal ideation among treated adolescents.

In a phase 3 trial involving 103 pediatric patients with congenital adrenal hyperplasia, crinecerfont treatment resulted in a mean reduction of androstenedione levels by 197 ng/dL after 4 weeks, compared to an increase of 71 ng/dL in the placebo group.

A recent study shows that combining meal replacement therapy with financial incentives led to a 6 percentage point greater reduction in BMI for adolescents with severe obesity compared to meal replacement therapy alone.

Genetic variants in the vitamin D pathway can lead to idiopathic infantile hypercalcemia, with CYP24A1 mutations being the most common cause.